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In a further experiment, the researchers inserted a gene into the hearts of the mice that increased the production of cGMP. The result: The mice were able to maintain normal heart function. Penile pain (11 to 32 percent) and minor urethral discomfort are the most common reported adverse effects of transurethral administration, with dizziness (2 percent) and symptomatic hypotension (3 percent) being the most serious.16 As with transcavernosal alprostadil, the transurethral form of the drug is contraindicated in patients with an abnormally formed penis, those having conditions that predispose them to priapism, those with a known hypersensitivity to alprostadil and those who have been advised for medical reasons to avoid sexual intercourse. Because it is a smooth muscle relaxant, transurethral alprostadil should not be used during sexual intercourse with a pregnant woman.16 Smoke What better, Viagra or Cialis? canadian viagra for sale online buy Viagra 120mg here canadian pharmacy viagra buy Viagra 200mg here viagra without prescription Return to text